ISCD Learning
Vertebral Augmentation and GLP1s Affect on Sarcopenia, MBD, OP (On-Demand)
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Register
- Non-Member - $35
- Full Member - $25
- Clinician Member - $25
- Technologist Member - $25
- Resident/Student/Fellow/Retired Membership - $25
- MOC Only - $35
- Community Member - $35
- Professional Member - $35
Activity approved for 1.00 AMA PRA Category 1 Credits™
Activity approved for 1.5 ASRT Category A Credits
Activity Expires October 14, 2027
Activity Description
Vertebral augmentation is an effective minimally invasive treatment for patients suffering from painful osteoporotic vertebral compression fractures. This presentation will review evidence-based indications for vertebral augmentation, with emphasis on clinical and imaging factors that guide optimal patient selection. We will examine short- and long-term outcomes data, including expected pain relief, functional improvement, and possible procedural risks. Practical, case-based insights will be shared to aid in every day clinical decision-making.
GLP-1 receptor agonists are now widely used for the management of diabetes and overweight/obesity. Concerns have been raised about their potential impact on skeletal muscle and bone density. This talk will look at the evidence to date regarding how this class of medication impacts bone and muscle health and will highlight future areas of investigation.
Learning Objectives
- Highlight the clinical impact of osteoporotic vertebral compression fractures (VCFs) and how they contribute to functional decline and mortality.
- Discuss inclusion criteria for vertebral augmentation to help identify candidates for referral/intervention.
- Review expected outcomes of vertebral augmentation, including effects on pain relief, functional improvement, and safety.
- Evaluate the risks, limitations, and controversies surrounding vertebral augmentation, including interpretation of existing trial data.
- Review the mechanism of action and indications for glucagon-like peptide-1 (GLP-1) receptor agonists
- Examine the impact of GLP-1s on skeletal muscle mass and function
- Examine the impact of GLP-1s on bone density and fracture risk
Instructions
Clinicians and Technologists are required to answer a set of online test questions following the review of the video and will have up to three attempts to answer questions correctly before losing credit for the activity. Once the activity test has been passed (75% or higher), you will be asked to evaluate the activity online and then be allowed to claim credit and print certificates.
Registration Fees
Cancellation Policy
On-Demand/ Enduring Material Cancellation
Purchases of on-demand or enduring educational materials are non-refundable.
On-Demand/Enduring Material Program Changes or Cancellations
ISCD reserves the right to cancel the program, change dates, and/or the location/method of offering. All program fees will be refunded if a program is canceled unless the registered participant elects to transfer to another program.
Joint Accreditation Statement

In support of improving patient care, this activity has been planned and implemented by Amedco LLC and ISCD. Amedco LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
AMA PRA Category 1 Credit(s)™
Amedco LLC designates this live activity for a maximum of 1.00 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
ASRT Credit Designation
This activity has been approved by ASRT for 1.5 Category A Continuing Education credits.
Date of Original Release and most recent Review or Update
This activity was most recently reviewed and released on October 15th, 2026.
Daniel J. Holzwanger, MD
Interventional Radiologist
Weill Cornell Medicine
Daniel J. Holzwanger, MD is an Interventional Radiologist and Assistant Professor of Clinical Radiology at Weill Cornell Medicine and New York-Presbyterian Hospital. He earned his medical degree from Weill Cornell Medical College and completed his Diagnostic Radiology residency at New York-Presbyterian/Weill Cornell Medical Center, where he served as Chief Resident. He subsequently completed fellowship training in Vascular and Interventional Radiology at Vanderbilt University Medical Center. His clinical practice focuses on image-guided musculoskeletal and spine interventions, including vertebral augmentation, tumor ablation, nerve ablation, and embolization therapies for pain and oncology care, with ongoing research aimed at advancing minimally invasive treatments for musculoskeletal and cancer-related pain.
Shirine E. Usmani, MD, PhD, FRCPC
Assistant Professor, Clinician Investigator and Staff Physician
University of Toronto, University Health Network, Toronto ON
Dr. Shirine Usmani completed her undergraduate degree in Physiology and Pharmacology at Western University before entering the MD/PhD program, also at Western. Her PhD focused on musculoskeletal health, specifically understanding molecular mechanisms involved in bone development and osteoarthritis. Dr. Usmani then went on to complete her residency training in Internal Medicine with a sub-specialization in Endocrinology at the University of Toronto. She completed a Post-Doctoral Fellowship through Toronto's Clinician Scientist Training Program with a focus on sarcopenia and genetic regulators of muscle mass. In October 2024 she started a full-time position as a Clinician Investigator/Assistant Professor at the University Health Network (UHN)/University of Toronto. Her research focuses on clinical and translational research through the UHN Osteoporosis and Metabolic Bone clinic.
Statement of Independence
The ISCD maintains a policy on the use of commercial support, which ensures that all educational activities sponsored by the ISCD provide in-depth presentations that are fair, balanced, independent, and scientifically rigorous. ISCD requires faculty, planners, managers, and other individuals and their spouse/life partner who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by ISCD for fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations. Individual disclosures are included in the course material. No Commercial Support has been provided for this activity
Disclaimer
The information and suggestions presented at the courses, seminars and other programs sponsored by ISCD and other collaborating societies are subject to change and therefore should serve only as a foundation for further investigation and study. Any forms presented at our seminars or programs are samples only and are not necessarily authoritative. All information, procedures, and forms contained or used in such seminars or programs should serve only as a guide for use in specific situations.
Disclosure of Unlabeled Use
This educational activity may contain a discussion of published and/or investigational uses of agents that are not indicated by the FDA. ISCD does not recommend the use of any agent outside of the labeled indications. The opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Privacy & Confidentiality Statement
The ISCD will record the learner’s personal information as provided on evaluations to allow for the issuance and tracking of CME/CE certificates. The ISCD may also track aggregate responses to questions in activities and evaluations and use these data to inform the ongoing evaluation and improvement of its educational program. No individual performance data or any other personal information collected for evaluations will be shared with third parties
Attendee Cancellation Policy
All changes in registration must be made in writing to [email protected]. Purchase of on-demand or enduring educational materials are non-refundable.
Course Changes or Cancellations
ISCD reserves the right to cancel the program and change the dates of the offering. All program fees will be refunded if a program is canceled unless the registered participant elects to transfer to another program.