ISCD Learning
Diagnosing Sarcopenia with DXA and Clinical Application of Bone Turnover Markers (On-Demand)
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- Non-Member - $35
- Full Member - $25
- MOC Only - $35
- Community Member - $35
- Professional Member - $35
Activity approved for 1.00 AMA PRA Category 1 Credits™
Activity approved for 1.5 ASRT Category A Credits
Activity Expires July 14, 2027
Activity Description
This talk will examine the role of DXA in diagnosing sarcopenia, highlighting its accessibility and value for estimating lean mass in clinical and research settings. It will critically discuss key limitations, including variability across devices, cut-off definitions, and the inability of DXA to capture muscle mass, quality and function. Practical implications for clinicians will be addressed, with guidance on how to interpret DXA findings within a comprehensive sarcopenia assessment. The second talk reviews the clinical application of bone turnover markers in osteoporosis management, with emphasis on monitoring response to oral bisphosphonate therapy. The lecture explains practical approaches for interpreting CTX, P1NP, and other markers to assess adherence, identify responders, and guide treatment decisions during and after therapy.
Learning Objectives:
- Differentiate sarcopenia as a disease from normal age-related changes in lean mass.
- Evaluate the clinical usefulness and limitations of DXA for assessing lean mass in suspected sarcopenia and osteosarcopenia.
- Describe emerging approaches and consensus efforts for defining and diagnosing sarcopenia, including the role of muscle mass, strength, and outcomes.
- Identify key sources of variability in bone turnover marker testing, including circadian rhythm, food intake, age, sex, and recent fracture.
- Apply least significant change and reference targets to determine whether a patient is responding to osteoporosis therapy.
- Use bone turnover markers to monitor adherence, treatment response, and offset of effect after oral bisphosphonate therapy.
Instructions:
Clinicians and Technologists are required to answer a set of online test questions following the review of the video and will have up to three attempts to answer questions correctly before losing credit for the activity. Once the activity test has been passed (75% or higher), you will be asked to evaluate the activity online and then be allowed to claim credit and print certificates.
Registration Fees
Cancellation Policy
On-Demand/ Enduring Material Cancellation
Purchases of on-demand or enduring educational materials are non-refundable.
On-Demand/Enduring Material Program Changes or Cancellations
ISCD reserves the right to cancel the program, change dates, and/or the location/method of offering. All program fees will be refunded if a program is canceled unless the registered participant elects to transfer to another program.
Joint Accreditation Statement:
In support of improving patient care, this activity has been planned and implemented by Amedco LLC and ISCD. Amedco LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
AMA PRA Category 1 Credit(s)™
Amedco LLC designates this live activity for a maximum of 1.00 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
ASRT Credit Designation
This activity has been approved by ASRT for 1.5 Category A Continuing Education credits.
Date of Original Release and most recent Review or Update
This activity was most recently reviewed and released on July 15th, 2026.
Gustavo Duque, MD, PhD, FRACP, FGSA
Professor of Medicine and Director of the Division of Geriatric Medicine
McGill University
Dr. Gustavo Duque, MD, PhD, FRACP, is a geriatrician and biomedical scientist with a research interest in the mechanisms, potential therapies, and biomarkers for age-related bone loss, osteoporosis, sarcopenia, osteosarcopenia, and frailty in older persons. He also studies the effects of vitamin D, exercise, and protein intake on bone and muscle mass.
His initial training included Internal Medicine at Javeriana University (Colombia) and Geriatric Medicine, which he completed at McGill University in Montreal (Canada). He obtained his PhD at McGill University in 2003 with a thesis entitled “Molecular Changes of the Aging Osteoblast” under the supervision of Dr. Richard Kremer. Between 2003 and November 2007, he joined the McGill University Medical School faculty as a member of the Division of Geriatric Medicine and as a Researcher at the Lady Davis Institute for Medical Research.
In November 2007, he moved to Australia to join the faculty as Associate Professor and Head of the Division of Geriatric Medicine and Director of the Musculoskeletal Ageing Research Program at Sydney Medical School Nepean, University of Sydney. In 2012, he was promoted to Professor of Medicine at the University of Sydney. Between 2015 and 2022, Dr. Duque held the positions of Chair of Medicine and Director of the Australian Institute for Musculoskeletal Science at the University of Melbourne.
In 2022, Dr. Duque assumed the roles of Full Professor, Dr. Joseph Kaufmann Chair in Geriatric Medicine, Director of the RUISSS McGill Centre of Excellence for Sustainable Health of Seniors/Simone & Edouard Shouela (CEDurable), and Principal Investigator in the Bone, Muscle & Geroscience Group at the Research Institute of the McGill University Health Centre (MUHC). He is also the Editor-in-Chief of the Journal of Gerontology: Biological Sciences, one of the official journals of the Gerontological Society of America. In 2025, he became Director of the McGill Division of Geriatric Medicine.
As a geriatrician and clinician-investigator, Dr. Duque has implemented several Falls and Fractures clinics—including the most recent at the McGill University Health Centre and the Jewish General Hospital in Montreal—where patients are comprehensively assessed for fall and fracture risk. His clinical trials unit conducts multiple studies evaluating pharmacological and non-pharmacological therapies for age-related musculoskeletal diseases. He is the author of more than 360 peer-reviewed articles and multiple book chapters and has edited five books in the aging and musculoskeletal fields, including two on osteosarcopenia.
Richard Eastell, MD
Professor and Head of the Academic Unit of Bone Metabolism
University of Sheffield
Dr. Richard Eastell is a Professor and Head of the Academic Unit of Bone Metabolism at the University of Sheffield–Sheffield Teaching Hospitals NHS Trust and Director of the Mellanby Centre for Bone Research in Sheffield, UK. He is an internationally recognized expert in osteoporosis, bone metabolism, and bone turnover markers.
Professor Eastell holds several prestigious positions including National Institute for Health Research Senior Investigator Emeritus status and serves on the International Osteoporosis Foundation Committee of Scientific Advisors. He has held leadership roles with the European Calcified Tissue Society (Program Co-Chair), serves as Treasurer for IBMS, and sits on editorial boards for Endocrine Reviews and Lancet Diabetes and Endocrinology. He also serves as Senior Editor for the journal Bone.
Statement of Independence
The ISCD maintains a policy on the use of commercial support, which ensures that all educational activities sponsored by the ISCD provide in-depth presentations that are fair, balanced, independent, and scientifically rigorous. ISCD requires faculty, planners, managers, and other individuals and their spouse/life partner who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by ISCD for fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations. Individual disclosures are included in the course material. No Commercial Support has been provided for this activity
Disclaimer
The information and suggestions presented at the courses, seminars and other programs sponsored by ISCD and other collaborating societies are subject to change and therefore should serve only as a foundation for further investigation and study. Any forms presented at our seminars or programs are samples only and are not necessarily authoritative. All information, procedures, and forms contained or used in such seminars or programs should serve only as a guide for use in specific situations.
Disclosure of Unlabeled Use
This educational activity may contain a discussion of published and/or investigational uses of agents that are not indicated by the FDA. ISCD does not recommend the use of any agent outside of the labeled indications. The opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Privacy & Confidentiality Statement
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Attendee Cancellation Policy
All changes in registration must be made in writing to education@iscd.org. Purchase of on-demand or enduring educational materials are non-refundable.
Course Changes or Cancellations
ISCD reserves the right to cancel the program and change the dates of the offering. All program fees will be refunded if a program is canceled unless the registered participant elects to transfer to another program.
